Psa 65:2 O You who hear prayer, To You all flesh will come.

1Th 5:17  pray without ceasing,

1Th 5:17
Pray without ceasing – Ye are dependent on God for every good; without him ye can do nothing; feel that dependence at all times, and ye will always be in the spirit of prayer; and those who feel this spirit will, as frequently as possible, be found in the exercise of prayer.
Adam Clarke’s Commentary on the Bible

Does anything more need to be said?  If we are always in the spirit of prayer and in the exercise of prayer He will hear.